What I Do: Brain Research, Big Data, and Machine Intelligence

Short Version

Inventor: Vaa3D, BrainAligner, NeuronTracers, SmartScope/SmartScope2, mRMR, 3D Virtual Finger, and more. Builder: cell and brain maps. Proponent: BioImage Informatics meetings, Brain Informatics conferences, journals (Bioinformatics, BMC Bioinformatics, and Brain Informatics), and BigNeuron and Open Interface of Bioimaging Software.

Long Version

I am interested in developing technologies to generate, manage, visualize, analyze, and understand massive-scale structure and function data related to brains, especially human brains. I am using approaches of Big Data and Machine Intelligence to study problems related to these topics. I am all for Open Science. I was with the Allen Institute for Brain Science (Seattle), and Janelia Research Campus, HHMI (Ashburn) in the last 15 years. I am also an affiliate/adjunct Professor with the University of Washington (USA) and the University of Georgia (USA), etc. Prior to 2006, I did research at Berkeley and Johns Hopkins, etc. I am an elected Fellow of AIMBE and IEEE.

We develop and use many machine learning, artificial intelligence, data mining, and imaging methods to handle the very complex and very large scale brain data, gene expression data, and many other types of data. We welcome collaborations especially the large scale data challenges. My group has been a world-leader in massive scale multi-dimensional imaging and visualization, very large scale brain mapping, neuron- and cell-phenotyping, feature extraction and Bayesian inferencing for general applications, as demonstrated in a number of high-profile, recognized publications and widely-used open-source software packages.

Some of my recent activities can be seen in the News and Media Reports, the Publications, or the Activities. A short BIO can be found here.