What I Do: Brain Big Data and more
Inventor: Vaa3D, BrainAligner, NeuronTracers, SmartScope/SmartScope2, mRMR, 3D Virtual Finger, and more. Builder: cell and brain maps. Proponent: BioImage Informatics meetings, Brain Informatics conferences, journals (Bioinformatics, BMC Bioinformatics, and Brain Informatics), and BigNeuron and Open Interface of Bioimaging Software. Location: allen institute @ Seattle and http://penglab.com
I am currently leading a Brain Big Data research group at the Allen Institute for Brain Science, Seattle, with the goal to develop revolutionary technologies to generate, manage, visualize, analyze, and understand massive-scale structure and function data related to brains, especially human brains. I also direct a newly established research center of Allen Institute at China, called Southeast University-Allen Institute Joint Research Center for Neuron Morphology (SEU-Allen), where we are doing a number of interesting projects. I am also an affiliate/adjunct faculty member (professor) with the University of Washington (USA) and the University of Georgia (USA), etc. Prior to my arrival at Seattle in the fall of 2012, I led a Big Image Mining research group at Janelia Research Campus, Howard Hughes Medical Institute, where I stayed for 7 years. Before then, I did research at a series of other interesting places, including for instance the Lawrence Berkeley National Laboratory, Johns Hopkins University Medical School, etc.
We develop and use many cutting-edge machine learning, artificial intelligence, data mining, and imaging methods to handle the very complex and very large scale brain data, gene expression data, and many other types of data. We welcome collaborations especially the large scale data challenges. Our group has been a world-leader in massive scale multi-dimensional imaging and visualization, very large scale brain mapping, neuron- and cell-phenotyping, feature extraction and Bayesian inferencing for general applications, as demonstrated in a number of high-profile, well-recognized publications and widely-used open-source software packages.